Prialt.com An effective non-opioid treatment option for severe chronic pain
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Unmet medical needs in IT pain management1-6

Patients may become refractory to IT therapy due to

  • Inadequate analgesia
  • Intolerable side effects
  • Drug-induced immune dysfunction and hormonal changes
  • Tolerance and dependence
  • Hyperalgesia
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Do you recognize this pattern?1-5

PRIALT is indicated for the management of severe chronic pain in patients for whom intrathecal (IT) therapy is warranted, and who are intolerant of or refractory to other treatment, such as systemic analgesics, adjunctive therapies or IT morphine.

Please see accompanying full prescribing information including boxed WARNING and important safety information.

References:

  1. Benyamin R, Trescot AM, Datta S, et al. Opioid complications and side effects. Pain Physician. 2008;11:S105-S120.
  2. Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003;349(20):1943-1953.
  3. Ballantyne JC. Opioids for chronic nonterminal pain. South Med J. 2006;99(11):1245-1255.
  4. Hassenbusch SJ, Garber J, Buchser E, Du Pen S, Nitescu P. Alternative intrathecal agents for the treatment of pain. Neuromodulation. 1999;2(2):85-91.
  5. Duramorph (morphine sulfate injection, USP) Prescribing Information. Baxter Healthcare Corporation. Deerfield, IL.
  6. Coffey RJ, Burchiel K. Inflammatory mass lesions associated with intrathecal drug infusion catheters: report and observation on 41 patients. Neurosurgery. 2002;50(1):78-87.